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Spyre Therapeutics Inc

SYRE

Latest QuantConomy context for SYRE: asset profile, market coverage, scored signals, and source-linked SEC insider filings when available.

Asset class
stock
Primary venue
NASDAQ
Recent signals
3
SEC filings
20
Asset profile

Spyre Therapeutics Inc

QuantConomy has a structured record for SYRE. More descriptive asset metadata will appear here when the platform record includes it.

Symbol
SYRE
Name
Spyre Therapeutics Inc
Coverage
3 market/data records
Sources
alpaca alphavantage fmp sec nasdaq
Latest signal rows

Recent signals for SYRE

Scored rows are pulled from the same signal API used by the digests.

Signal Direction Score Observed Reason
volume
volume spike
neutral
41
Jul 10, 05:37 PM SYRE volume spike: 386% of expected volume for Friday 17:00 UTC, price flat 0.09% (strength 41)
volume
volume spike
neutral
40
Jul 10, 04:35 PM SYRE volume spike: 345% of expected volume for Friday 16:00 UTC, price flat 0.06% (strength 40)
price
downtrend
slightly bearish
27
Jul 10, 03:37 PM SYRE downtrend (drop): price -1.37% (strength 27, current 97.42)

EARNINGS signals are experimental: currently limited to neutral pre-earnings calendar awareness (no transcript analysis).

PROPOSED_SALE signals are experimental: historical Form 144 coverage is still being backfilled, so results may be sparse or empty.

Market coverage

Market Exchange Source Asset record
SYRE NASDAQ alpaca Spyre Therapeutics, Inc. Common Stock
SYRE NASDAQ alphavantage Spyre Therapeutics Inc
SYRE NASDAQ fmp Spyre Therapeutics, Inc.

Recent insider transactions

Buys, last 90d
0
Sells, last 90d
5
Rows
20
Date Insider Role Type Shares Price Value Filing
Jul 1, 2026 Sloan Sheldon Chief Medical Officer exercise 8,334 $27.46 $228,852 4 on EDGAR
Jul 1, 2026 Burrows Scott L Chief Financial Officer exercise 7,500 $14.50 $108,750 4 on EDGAR
Jul 1, 2026 Turtle Cameron Chief Executive Officer sale 10,176 $87.44 $889,789 4 on EDGAR
Jun 25, 2026 Burrows Scott L Chief Financial Officer exercise 15,000 $14.50 $217,500 4 on EDGAR
Jun 23, 2026 Fairmount Funds Management LLC Insider other 666,680 4 on EDGAR
Jun 22, 2026 HENDERSON MICHAEL THOMAS Insider sale 20,000 $100.00 $2,000,000 4 on EDGAR
Jun 3, 2026 Sloan Sheldon Chief Medical Officer exercise 8,333 $27.46 $228,824 4 on EDGAR
Jun 1, 2026 Burrows Scott L Chief Financial Officer exercise 7,500 $14.50 $108,750 4 on EDGAR
Jun 1, 2026 Turtle Cameron Chief Executive Officer sale 3,557 $69.40 $246,856 4 on EDGAR
May 27, 2026 Milligan Sandra Insider grant 8,026 4 on EDGAR
May 27, 2026 HENDERSON MICHAEL THOMAS Insider grant 8,026 4 on EDGAR
May 27, 2026 Fairmount Funds Management LLC Insider grant 8,026 4 on EDGAR
May 27, 2026 Albers Jeffrey W. Insider grant 8,026 4 on EDGAR
May 27, 2026 Stelzer Laurie Insider grant 8,026 4 on EDGAR
May 27, 2026 McKenna Mark C. Insider grant 8,026 4 on EDGAR
May 8, 2026 HENDERSON MICHAEL THOMAS Insider sale 2,404 $72.57 $174,458 4 on EDGAR
May 1, 2026 Sloan Sheldon Chief Medical Officer exercise 78,333 $27.46 $2,151,024 4 on EDGAR
May 1, 2026 Turtle Cameron Chief Executive Officer sale 5,300 $69.54 $368,562 4 on EDGAR
May 1, 2026 Burrows Scott L Chief Financial Officer exercise 12,500 $14.50 $181,250 4 on EDGAR
Apr 1, 2026 Sloan Sheldon Chief Medical Officer exercise 7,958 $21.66 $172,370 4 on EDGAR

Source: SEC filings via QuantConomy. Not investment advice.

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